Adenosine residues in the template do not block spontaneous replication steps of RNA

Stephanie R. Vogel; Clemens Richert

doi:10.1039/B702768K

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Chemical Communications

Issue 19, 2007

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Adenosine residues in the template do not block spontaneous replication steps of RNA

Stephanie R. Vogel and Clemens Richert

Chem. Commun., 2007, 1896-1898

DOI: 10.1039/B702768K
Received 22 Feb 2007, Accepted 20 Mar 2007
First published on the web 12 Apr 2007

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Sub-freezing temperatures, azabenzotriazolide activation, multiple monomer addition, and helper displacement help to overcome what seemed like an intrinsic block of adenine-templated RNA replication steps in the absence of enzymes.

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Chemical Communications

Adenosine residues in the template do not block spontaneous replication steps of RNA

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