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Issue 27, 2007
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The relationships between oxidase and synthase activities of flavin dependent thymidylate synthase (FDTS)

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Abstract

New findings lead to a revised understanding of the substrates' binding order, the role of the substrate as an activator, and the observed lag phase in the FDTS catalyzed reaction.

Graphical abstract: The relationships between oxidase and synthase activities of flavin dependent thymidylate synthase (FDTS)

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Publication details

The article was received on 22 Jan 2007, accepted on 10 Apr 2007 and first published on 25 Apr 2007


Article type: Communication
DOI: 10.1039/B700977A
Citation: Chem. Commun., 2007,0, 2861-2863
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    The relationships between oxidase and synthase activities of flavin dependent thymidylate synthase (FDTS)

    A. Chernyshev, T. Fleischmann, E. M. Koehn, S. A. Lesley and A. Kohen, Chem. Commun., 2007, 0, 2861
    DOI: 10.1039/B700977A

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