Jump to main content
Jump to site search

Issue 1, 2007
Previous Article Next Article

Chemistry and biology of resorcylic acid lactones

Author affiliations

Abstract

While resorcylic acid lactones (RALs) have been known for a long time, the more recent discoveries that radicicol is a potent and selective HSP90 inhibitor while other members such as hypothemycin, LL-Z1640-2 and LL-783,277 are potent kinase inhibitorshave stimulated a renewed interest in this family of natural products. The recent developments regarding the chemistry and biology of RALs are reviewed.

Graphical abstract: Chemistry and biology of resorcylic acid lactones

Back to tab navigation

Publication details

The article was received on 19 Jul 2006, accepted on 18 Aug 2006 and first published on 25 Sep 2006


Article type: Feature Article
DOI: 10.1039/B610344H
Citation: Chem. Commun., 2007,0, 22-36
  •   Request permissions

    Chemistry and biology of resorcylic acid lactones

    N. Winssinger and S. Barluenga, Chem. Commun., 2007, 0, 22
    DOI: 10.1039/B610344H

Search articles by author

Spotlight

Advertisements