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Issue 4, 2007
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Mass spectrometric identification of peptidehormones in doping-control analysis

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Abstract

The identification power of mass spectrometry has enabled the determination of hundreds of prohibited drugs in doping-control analysis. A few years ago, its utility was extended to peptidehormones such as erythropoietins, synthetic insulins and corticotrophins detectable in blood or urine. New assays have been established to improve the fight against doping, employing highly selective and sensitive detection methods based on chromatographic and tandem mass spectrometric techniques. In particular, in light of recent scandals related to assumed peptidehormone misuse and attempts at the alteration of urine, sophisticated analytical tools are essential for obtaining unequivocal results in sports drug testing.

Graphical abstract: Mass spectrometric identification of peptidehormones in doping-control analysis

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Publication details

The article was received on 22 Dec 2006, accepted on 21 Feb 2007 and first published on 05 Mar 2007


Article type: Highlight
DOI: 10.1039/B618748J
Citation: Analyst, 2007,132, 287-291
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    Mass spectrometric identification of peptidehormones in doping-control analysis

    M. Thevis and W. Schänzer, Analyst, 2007, 132, 287
    DOI: 10.1039/B618748J

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