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Issue 19, 2006
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Rapamycin biosynthesis: elucidation of gene product function

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Abstract

The function of gene products involved in the biosynthesis of the clinically important polyketide rapamycin were elucidated by biotransformation and gene complementation

Graphical abstract: Rapamycin biosynthesis: elucidation of gene product function

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Publication details

The article was received on 21 Jun 2006, accepted on 11 Aug 2006 and first published on 22 Aug 2006


Article type: Communication
DOI: 10.1039/B608813A
Citation: Org. Biomol. Chem., 2006,4, 3565-3568
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    Rapamycin biosynthesis: elucidation of gene product function

    M. A. Gregory, H. Hong, R. E. Lill, S. Gaisser, H. Petkovic, L. Low, L. S. Sheehan, I. Carletti, S. J. Ready, M. J. Ward, A. L. Kaja, A. J. Weston, I. R. Challis, P. F. Leadlay, C. J. Martin, B. Wilkinson and R. M. Sheridan, Org. Biomol. Chem., 2006, 4, 3565
    DOI: 10.1039/B608813A

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