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Issue 12, 2006
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Analysis of the reactions used for the preparation of drug candidate molecules

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Abstract

The purpose of this perspective is to indicate the range of chemistries used in the manufacture of drug candidate molecules and to highlight certain gaps in current technologies. To do this a survey was carried out of chemical syntheses within the Process Chemistry R&D departments of GlaxoSmithKline, AstraZeneca and Pfizer.

Graphical abstract: Analysis of the reactions used for the preparation of drug candidate molecules

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Publication details

The article was received on 16 Feb 2006 and first published on 03 May 2006


Article type: Perspective
DOI: 10.1039/B602413K
Citation: Org. Biomol. Chem., 2006,4, 2337-2347
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    Analysis of the reactions used for the preparation of drug candidate molecules

    J. S. Carey, D. Laffan, C. Thomson and M. T. Williams, Org. Biomol. Chem., 2006, 4, 2337
    DOI: 10.1039/B602413K

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