Issue 12, 2006

Analysis of the reactions used for the preparation of drug candidate molecules

Abstract

The purpose of this perspective is to indicate the range of chemistries used in the manufacture of drug candidate molecules and to highlight certain gaps in current technologies. To do this a survey was carried out of chemical syntheses within the Process Chemistry R&D departments of GlaxoSmithKline, AstraZeneca and Pfizer.

Graphical abstract: Analysis of the reactions used for the preparation of drug candidate molecules

Article information

Article type
Perspective
Submitted
16 Feb 2006
First published
03 May 2006

Org. Biomol. Chem., 2006,4, 2337-2347

Analysis of the reactions used for the preparation of drug candidate molecules

J. S. Carey, D. Laffan, C. Thomson and M. T. Williams, Org. Biomol. Chem., 2006, 4, 2337 DOI: 10.1039/B602413K

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