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Issue 23, 2006
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Enzyme-responsive materials: a new class of smart biomaterials

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Abstract

Enzyme-responsive materials (ERMs) are a new class of smart materials that undergo macroscopic transitions when triggered by selective catalytic actions of enzymes. The use of enzymes as stimuli to trigger mechanical responses in materials opens up a number of possible applications in biology and medicine. Three different classes of ERMs are described, based on supramolecular assemblies, chemically crosslinked gels and (nanoparticle) surfaces. Potential applications in regenerative medicine, diagnostics, and drug delivery are discussed.

Graphical abstract: Enzyme-responsive materials: a new class of smart biomaterials

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Publication details

The article was received on 06 Feb 2006, accepted on 24 Mar 2006 and first published on 18 Apr 2006


Article type: Feature Article
DOI: 10.1039/B601776M
Citation: J. Mater. Chem., 2006,16, 2217-2225
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    Enzyme-responsive materials: a new class of smart biomaterials

    R. V. Ulijn, J. Mater. Chem., 2006, 16, 2217
    DOI: 10.1039/B601776M

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