Issue 11, 2006

A green route to β-amino alcohols via the uncatalyzed aminolysis of 1,2-epoxides by alkyl- and arylamines

Abstract

Under mildly basic and pH-controlled aqueous conditions the aminolysis of 1,2-epoxides 1a–g by alkyl- and arylamines 2a–k is generally highly regioselective giving the corresponding β-amino alcohols in satisfactory to excellent yields.

Graphical abstract: A green route to β-amino alcohols via the uncatalyzed aminolysis of 1,2-epoxides by alkyl- and arylamines

Article information

Article type
Paper
Submitted
30 May 2006
Accepted
18 Jul 2006
First published
10 Aug 2006

Green Chem., 2006,8, 960-964

A green route to β-amino alcohols via the uncatalyzed aminolysis of 1,2-epoxides by alkyl- and arylamines

S. Bonollo, F. Fringuelli, F. Pizzo and L. Vaccaro, Green Chem., 2006, 8, 960 DOI: 10.1039/B607620C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements