Issue 1, 2006
From the journal:

Green Chemistry

A green and facile route to γ- and δ-lactones via efficient Pinner-cyclization of hydroxynitriles in water†

Karolina Aplander,a   Olle Hidestål,a   Kambiz Katebzadeha  and  Ulf M. Lindström*a  

* Corresponding authors

a Organic Chemistry, Lund University, P. O. Box 124, SE-221 00 Lund, Sweden
E-mail: ulf.lindstrom@organic.lu.se
Fax: +46 46 2228209
Tel: +46 46 2228211

Abstract

In the presence of a recyclable cationic exchange resin hydroxynitriles smoothly undergo a Pinner cyclization/hydrolysis two-step reaction in pure water to give lactones in good to excellent yields.

Graphical abstract: A green and facile route to γ- and δ-lactones via efficient Pinner-cyclization of hydroxynitriles in water

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Article information

DOI
https://doi.org/10.1039/B513656C
Article type
Communication
Submitted
26 Sep 2005
Accepted
16 Nov 2005
First published
23 Nov 2005

Green Chem., 2006,8, 22-24

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A green and facile route to γ- and δ-lactones via efficient Pinner-cyclization of hydroxynitriles in water

K. Aplander, O. Hidestål, K. Katebzadeh and U. M. Lindström, Green Chem., 2006, 8, 22 DOI: 10.1039/B513656C

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