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Issue 11, 2006
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Imparting size, shape, and composition control of materials for nanomedicine

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Abstract

This tutorial review presents an overview of strategies for the synthesis and fabrication of organic nanomaterials, specifically those with potential for use in medical applications. Examples include liposomes, micelles, polymerdrug conjugates and dendrimers. Methods of driving shape via “bottom-up” synthetic approaches and thermodynamics and kinetics are discussed. Furthermore, methods of driving shape via “top-down” physical and engineering techniques are also explored. Finally, a novel method (referred to as PRINT) used to produce nanoparticles that are shape-specific, can contain any cargo, and can be easily modified is examined along with its potential future role in nanomedicine.

Graphical abstract: Imparting size, shape, and composition control of materials for nanomedicine

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Publication details

The article was received on 20 Jul 2006 and first published on 20 Sep 2006


Article type: Tutorial Review
DOI: 10.1039/B600913C
Citation: Chem. Soc. Rev., 2006,35, 1095-1104
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    Imparting size, shape, and composition control of materials for nanomedicine

    L. E. Euliss, J. A. DuPont, S. Gratton and J. DeSimone, Chem. Soc. Rev., 2006, 35, 1095
    DOI: 10.1039/B600913C

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