Using enzymatic reactions to enhance the photodynamic therapy effect of porphyrin dityrosine phosphates

Gaolin Liang; Ling Wang; Zhimou Yang; Hokee Koon; Naiki Mak; Chi K. Chang; Bing Xu

doi:10.1039/B611557H

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Chemical Communications

Issue 48, 2006

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Using enzymatic reactions to enhance the photodynamic therapy effect of porphyrin dityrosine phosphates

Gaolin Liang , Ling Wang , Zhimou Yang , Hokee Koon , Naiki Mak , Chi K. Chang and Bing Xu

Chem. Commun., 2006, 5021-5023

DOI: 10.1039/B611557H
Received 10 Aug 2006, Accepted 26 Sep 2006
First published on the web 12 Oct 2006

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This paper reports the synthesis and photodynamic therapy (PDT) effect of a porphyrin derivative containing tyrosine phosphate, which promises a new, useful approach to develop PDT agents.

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Synthesis, in vitro conversion of 3, location of 2 in cells, and dark and photo cytotoxicity of 3
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Gaolin Liang
Ling Wang
Zhimou Yang
Hokee Koon
Naiki Mak
Chi K. Chang
Bing Xu

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Chemical Communications

Using enzymatic reactions to enhance the photodynamic therapy effect of porphyrin dityrosine phosphates

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