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Issue 24, 2006
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A flow process for the multi-step synthesis of the alkaloid natural product oxomaritidine: a new paradigm for molecular assembly

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Abstract

A flow process for the multi-step synthesis of the alkaloid natural product (±)-oxomaritidine is described, mediated through the use of microfluidic pumping systems that progress material through various packed columns containing immobilized reagents, catalysts, scavengers or catch and release agents; our route involves the combination of seven separate synthetic steps linked into one continuous sequence utilizing flow chemistry.

Graphical abstract: A flow process for the multi-step synthesis of the alkaloid natural product oxomaritidine: a new paradigm for molecular assembly

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Publication details

The article was received on 11 Jan 2006, accepted on 03 Feb 2006 and first published on 24 Mar 2006


Article type: Communication
DOI: 10.1039/B600382F
Citation: Chem. Commun., 2006,0, 2566-2568
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    A flow process for the multi-step synthesis of the alkaloid natural product oxomaritidine: a new paradigm for molecular assembly

    I. R. Baxendale, J. Deeley, C. M. Griffiths-Jones, S. V. Ley, S. Saaby and G. K. Tranmer, Chem. Commun., 2006, 0, 2566
    DOI: 10.1039/B600382F

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