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Issue 6, 2006
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Fluorinase mediated C–18F bond formation, an enzymatic tool for PET labelling

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Abstract

The fluorinase enzyme from S. cattleya is applied as a catalyst for the efficient incorporation of [18F]-fluoride into [18F]-5′-fluoro-5′-deoxyadenosine, [18F]-5′-fluoro-5′-deoxyinosine and [18F]-5-fluoro-5-deoxyribose for positron emission tomography (PET) applications.

Graphical abstract: Fluorinase mediated C–18F bond formation, an enzymatic tool for PET labelling

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Publication details

The article was received on 28 Nov 2005, accepted on 10 Jan 2006 and first published on 18 Jan 2006


Article type: Communication
DOI: 10.1039/B516861A
Citation: Chem. Commun., 2006,0, 652-654
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    Fluorinase mediated C–18F bond formation, an enzymatic tool for PET labelling

    H. Deng, S. L. Cobb, A. D. Gee, A. Lockhart, L. Martarello, R. P. McGlinchey, D. O'Hagan and M. Onega, Chem. Commun., 2006, 0, 652
    DOI: 10.1039/B516861A

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