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Issue 7, 2006
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Activity-based high-throughput profiling of metalloprotease inhibitors using small molecule microarrays

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Abstract

We herein describe a high-throughput small molecule microarray (SMM) method that enables quick and cost-effective identification of potent inhibitors of metalloproteases in an activity-dependent manner, thereby offering a rapid means for inhibitor discovery and profiling.

Graphical abstract: Activity-based high-throughput profiling of metalloprotease inhibitors using small molecule microarrays

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Publication details

The article was received on 27 Oct 2005, accepted on 01 Dec 2005 and first published on 04 Jan 2006


Article type: Communication
DOI: 10.1039/B515278J
Citation: Chem. Commun., 2006, 717-719
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    Activity-based high-throughput profiling of metalloprotease inhibitors using small molecule microarrays

    J. Wang, M. Uttamchandani, L. P. Sun and S. Q. Yao, Chem. Commun., 2006, 717
    DOI: 10.1039/B515278J

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