Issue 30, 2006

Site-specific transition of cytosine to uracilvia reversible DNA photoligation

Abstract

We report that deamination coupled with 5-carboxyvinyldeoxyuridine-mediated photobranching causes the heat-induced transition of cytosine to uracil with high efficiency without any side reaction.

Graphical abstract: Site-specific transition of cytosine to uracil via reversible DNA photoligation

Supplementary files

Article information

Article type
Communication
Submitted
12 Apr 2006
Accepted
06 Jun 2006
First published
21 Jun 2006

Chem. Commun., 2006, 3223-3225

Site-specific transition of cytosine to uracil via reversible DNA photoligation

K. Fujimoto, S. Matsuda, Y. Yoshimura, T. Matsumura, M. Hayashi and I. Saito, Chem. Commun., 2006, 3223 DOI: 10.1039/B605289D

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