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Issue 21, 2006
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Easy access to the family of thiazole N-oxides using HOF·CH3CN

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Abstract

An efficient procedure for transferring an oxygen atom to thiazole-containing compounds, resulting in the corresponding N-oxides, was developed by using HOF·CH3CN; mild reaction conditions, high yields and easy purification are the main features of this novel route, while X-ray structural analysis reveals a hydrogen bond between the N-oxide functionality and a water molecule.

Graphical abstract: Easy access to the family of thiazole N-oxides using HOF·CH3CN

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Publication details

The article was received on 21 Feb 2006, accepted on 05 Apr 2006 and first published on 25 Apr 2006


Article type: Communication
DOI: 10.1039/B602594C
Citation: Chem. Commun., 2006,0, 2262-2264
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    Easy access to the family of thiazole N-oxides using HOF·CH3CN

    E. Amir and S. Rozen, Chem. Commun., 2006, 0, 2262
    DOI: 10.1039/B602594C

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