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Issue 10, 2006
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The role of biosensors in the detection of emerging infectious diseases

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Abstract

Global biosecurity threats such as the spread of emerging infectious diseases (i.e., avian influenza, SARS, Hendra, Nipah, etc.) and bioterrorism have generated significant interest in recent years. There is considerable effort directed towards understanding and negating the proliferation of infectious diseases. Biosensors are an attractive tool which have the potential to detect the outbreak of a virus and/or disease. Although there is a host of technologies available, either commercially or in the scientific literature, the development of biosensors for the detection of emerging infectious diseases (EIDs) is still in its infancy. There is no doubt that the glucose biosensor, the gene chip, the protein chip, etc. have all played and are still playing a significant role in monitoring various biomolecules. Can biosensors play an important role for the detection of emerging infectious diseases? What does the future hold and which biosensor technology platform is suitable for the real-time detection of infectious diseases? These and many other questions will be addressed in this review. The purpose of this review is to present an overview of biosensors particularly in relation to EIDs. It provides a synopsis of the various types of biosensor technologies that have been used to detect EIDs, and describes some of the technologies behind them in terms of transduction and bioreceptor principles.

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases

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Publication details

The article was received on 07 Mar 2006, accepted on 28 Jun 2006 and first published on 11 Jul 2006


Article type: Critical Review
DOI: 10.1039/B603402K
Citation: Analyst, 2006,131, 1079-1090
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    The role of biosensors in the detection of emerging infectious diseases

    B. Pejcic, R. D. Marco and G. Parkinson, Analyst, 2006, 131, 1079
    DOI: 10.1039/B603402K

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