Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance upgrade on Thursday 4th of May 2017 from 8.00am to 9.00am (BST).

During this time our websites will be offline temporarily. If you have any questions please use the feedback button on this page. We apologise for any inconvenience this might cause and thank you for your patience.


Issue 3, 2006
Previous Article Next Article

NMR studies of organic polymorphs & solvates

Author affiliations

Abstract

This review article describes the applications of NMR to the study of polymorphs and related forms (solvates) of organic (especially pharmaceutical) compounds, for which it is of increasing academic and practical importance. The nature of the systems covered is briefly introduced, as are the techniques constituting solid-state NMR. The methodologies involved are then reviewed under a number of different headings, ranging from spectral editing through relaxation times to shielding tensors and NMR crystallography. In each case the relevant applications are described. Whilst most studies concentrate on structural matters, motional effects are not neglected. A special section discusses studies of solvates (especially hydrates), and another reviews quantitative analysis.

Graphical abstract: NMR studies of organic polymorphs & solvates

Back to tab navigation
Please wait while Download options loads

Publication details

The article was received on 11 Nov 2005, accepted on 09 Dec 2005 and first published on 20 Jan 2006


Article type: Critical Review
DOI: 10.1039/B516057J
Citation: Analyst, 2006,131, 351-373
  •   Request permissions

    NMR studies of organic polymorphs & solvates

    R. K. Harris, Analyst, 2006, 131, 351
    DOI: 10.1039/B516057J

Search articles by author