Jump to main content
Jump to site search

Issue 24, 2005
Previous Article Next Article

Recognition and activation by ureas and thioureas: stereoselective reactions using ureas and thioureas as hydrogen-bonding donors

Author affiliations

Abstract

Hydrogen-bonding interaction plays a crucial role in the molecular recognition and activation processes of various biologically important reactions that are mediated by enzymes and antibodies in living organisms. Recently, it has been shown that a hydrogen-bonding donor can be used as a general acid catalyst for various types of reactions in organic chemistry. In this article, we describe enantioselective reactions catalyzed by urea and thiourea derivatives as general acid catalysts as well as diastereoselective reactions. This perspective provides an overview of this rapidly growing field.

Graphical abstract: Recognition and activation by ureas and thioureas: stereoselective reactions using ureas and thioureas as hydrogen-bonding donors

Back to tab navigation
Please wait while Download options loads

Publication details

The article was received on 05 Aug 2005, accepted on 28 Sep 2005 and first published on 20 Oct 2005


Article type: Perspective
DOI: 10.1039/B511216H
Citation: Org. Biomol. Chem., 2005,3, 4299-4306
  •   Request permissions

    Recognition and activation by ureas and thioureas: stereoselective reactions using ureas and thioureas as hydrogen-bonding donors

    Y. Takemoto, Org. Biomol. Chem., 2005, 3, 4299
    DOI: 10.1039/B511216H

Search articles by author