Jump to main content
Jump to site search

Issue 11, 2005
Previous Article Next Article

1-Ethynylpyrene-modified guanine and cytosine as optical labels for DNA hybridization

Author affiliations

Abstract

1-Ethynylpyrene shows remarkable absorption changes upon DNA hybridization when it is covalently attached to the 8-position of guanine. An absorption band at ∼420 nm is only present in the duplex, exhibits thermal melting behaviour and provides the basis for a molecular beacon together with 1-ethynylpyrene-modified cytosine.

Graphical abstract: 1-Ethynylpyrene-modified guanine and cytosine as optical labels for DNA hybridization

Back to tab navigation

Supplementary files

Publication details

The article was received on 21 Mar 2005, accepted on 19 Apr 2005 and first published on 04 May 2005


Article type: Communication
DOI: 10.1039/B504079E
Citation: Org. Biomol. Chem., 2005,3, 2062-2063
  •   Request permissions

    1-Ethynylpyrene-modified guanine and cytosine as optical labels for DNA hybridization

    C. Wagner, M. Rist, E. Mayer-Enthart and H. Wagenknecht, Org. Biomol. Chem., 2005, 3, 2062
    DOI: 10.1039/B504079E

Search articles by author

Spotlight

Advertisements