Issue 8, 2005
From the journal:

New Journal of Chemistry

A catalyst for an acetal hydrolysis reaction from a dynamic combinatorial library

Laurent Vial,a   Jeremy K. M. Sandersa  and  Sijbren Otto*a  

* Corresponding authors

a Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, UK
E-mail: so230@cam.ac.uk
Fax: +44 1223 336017
Tel: +44 1223 336509

Abstract

A transition-state analogue (TSA) for an acetal hydrolysis reaction was found to select and amplify a macrocycle from a dynamic combinatorial library (DCL) of disulfides in water. This host was able to accelerate the reaction by a factor of two; a similar value was progressively reached when the macrocycle was gradually produced in the course of the reaction.

Graphical abstract: A catalyst for an acetal hydrolysis reaction from a dynamic combinatorial library

About
Cited by
Related
Download options Please wait...

Article information

DOI
https://doi.org/10.1039/B505316A
Article type
Letter
Submitted
15 Apr 2005
Accepted
16 Jun 2005
First published
01 Jul 2005

New J. Chem., 2005,29, 1001-1003

Permissions

Request permissions

A catalyst for an acetal hydrolysis reaction from a dynamic combinatorial library

L. Vial, J. K. M. Sanders and S. Otto, New J. Chem., 2005, 29, 1001 DOI: 10.1039/B505316A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements