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Issue 3, 2005
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Nucleoside phosphocholine amphiphile for in vitro DNA transfection

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Abstract

A new transfection reagent based on nucleoside phosphocholine amphiphile leading to high transfection efficacy and low cytotoxicity is described. TEM, ethidium bromide displacement assays, agarose gel electrophoresis and SAXS studies support the formation of lipoplexes for the transfection of CHO cells.

Graphical abstract: Nucleoside phosphocholine amphiphile for in vitro DNA transfection

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Publication details

The article was received on 08 Mar 2005, accepted on 30 Jun 2005 and first published on 22 Jul 2005


Article type: Paper
DOI: 10.1039/B503302K
Citation: Mol. BioSyst., 2005,1, 260-264
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    Nucleoside phosphocholine amphiphile for in vitro DNA transfection

    L. Moreau, P. Barthélémy, Y. Li, D. Luo, C. A. H. Prata and M. W. Grinstaff, Mol. BioSyst., 2005, 1, 260
    DOI: 10.1039/B503302K

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