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Issue 10, 2005
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Electroosmotic flow analysis of a branched U-turn nanofluidic device

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Abstract

In this paper, we present the analysis of electroosmotic flow in a branched U-turn nanofluidic device, which we developed for detection and sorting of single molecules. The device, where the channel depth is only 150 nm, is designed to optically detect fluorescence from a volume as small as 270 attolitres (al) with a common wide-field fluorescent setup. We use distilled water as the liquid, in which we dilute 110 nm fluorescent beads employed as tracer-particles. Quantitative imaging is used to characterize the pathlines and velocity distribution of the electroosmotic flow in the device. Due to the device's complex geometry, the electroosmotic flow cannot be solved analytically. Therefore we use numerical flow simulation to model our device. Our results show that the deviation between measured and simulated data can be explained by the measured Brownian motion of the tracer-particles, which was not incorporated in the simulation.

Graphical abstract: Electroosmotic flow analysis of a branched U-turn nanofluidic device

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Publication details

The article was received on 19 Apr 2005, accepted on 20 Jun 2005 and first published on 18 Jul 2005


Article type: Paper
DOI: 10.1039/B505493A
Citation: Lab Chip, 2005,5, 1067-1074
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    Electroosmotic flow analysis of a branched U-turn nanofluidic device

    G. O. F. Parikesit, A. P. Markesteijn, V. G. Kutchoukov, O. Piciu, A. Bossche, J. Westerweel, Y. Garini and I. T. Young, Lab Chip, 2005, 5, 1067
    DOI: 10.1039/B505493A

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