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Issue 3, 2005
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Computer-aided organic synthesis

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Abstract

It is tempting for those in the field of organic synthesis to liken the process of retrosynthesis to a game of chess. That the world chess champion was recently defeated by a computer leads us to think that perhaps new and powerful computing methods could be applied to synthetic problems. Here the analogy between synthesis and chess is outlined. Achievements in the 35-year history of computer-aided synthetic design are described, followed by some more recent developments.

Graphical abstract: Computer-aided organic synthesis

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Publication details

The article was received on 10 Sep 2004 and first published on 08 Feb 2005


Article type: Tutorial Review
DOI: 10.1039/B104620A
Citation: Chem. Soc. Rev., 2005,34, 247-266
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    Computer-aided organic synthesis

    M. H. Todd, Chem. Soc. Rev., 2005, 34, 247
    DOI: 10.1039/B104620A

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