Jump to main content
Jump to site search

Issue 38, 2005
Previous Article Next Article

Organocatalytic asymmetric α-bromination of aldehydes and ketones

Author affiliations

Abstract

The first organocatalytic enantioselective α-bromination of aldehydes and ketones is presented; a C2-symmetric diphenylpyrrolidine catalyst afforded the α-brominated aldehydes in good yields and up to 96% ee, while ketones were α-brominated by a C2-symmetric imidazolidine in up to 94% ee; furthermore, the organocatalytic enantioselective α-iodination of aldehydes is also demonstrated to proceed with up to 89% ee.

Graphical abstract: Organocatalytic asymmetric α-bromination of aldehydes and ketones

Back to tab navigation

Supplementary files

Publication details

The article was received on 01 Jul 2005, accepted on 26 Jul 2005 and first published on 30 Aug 2005


Article type: Communication
DOI: 10.1039/B509366J
Citation: Chem. Commun., 2005,0, 4821-4823
  •   Request permissions

    Organocatalytic asymmetric α-bromination of aldehydes and ketones

    S. Bertelsen, N. Halland, S. Bachmann, M. Marigo, A. Braunton and K. A. Jørgensen, Chem. Commun., 2005, 0, 4821
    DOI: 10.1039/B509366J

Search articles by author

Spotlight

Advertisements