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Issue 34, 2005
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Structure elucidation of a novel family of mycolactone toxins from the frog pathogen Mycobacterium sp. MU128FXT by mass spectrometry

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Abstract

Structures are proposed, based on LC-ion trap MSn analysis and high-resolution FTICR MS/MS analysis, for a novel family of mycolactone toxins isolated from the frog pathogen MU128FXT and differing from those produced by the human pathogen M. ulcerans MUAgy99 in having an altered polyketide side chain.

Graphical abstract: Structure elucidation of a novel family of mycolactone toxins from the frog pathogen Mycobacterium sp. MU128FXT by mass spectrometry

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Publication details

The article was received on 17 May 2005, accepted on 29 Jun 2005 and first published on 05 Aug 2005


Article type: Communication
DOI: 10.1039/B506835E
Citation: Chem. Commun., 2005, 4306-4308
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    Structure elucidation of a novel family of mycolactone toxins from the frog pathogen Mycobacterium sp. MU128FXT by mass spectrometry

    H. Hong, T. Stinear, P. Skelton, J. B. Spencer and P. F. Leadlay, Chem. Commun., 2005, 4306
    DOI: 10.1039/B506835E

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