Issue 36, 2005
From the journal:

Chemical Communications

A ligand-free solid-supported system for Sonogashira couplings: applications in nucleoside chemistry†

Neil K. Garg,a   Carolyn C. Woodroofe,a   Christopher J. Lacenere,b   Stephen R. Quake‡*c  and  Brian M. Stoltz*a  

* Corresponding authors

a Division of Chemistry and Chemical Engineering, California Institute of Technology, 1200 East California Boulevard, MC 164-30, Pasadena, USA
E-mail: stoltz@caltech.edu
Fax: +1 626 564 9297
Tel: +1 626 395 6064

b Division of Biology, California Institute of Technology, 1200 East California Boulevard, Pasadena, USA

c Division of Engineering and Applied Science, California Institute of Technology, 1200 East California Boulevard, Pasadena, USA

Abstract

A mild heterogeneous, ligand-free protocol for Sonogashira and Heck couplings has been developed and used to access several biologically important deoxynucleoside derivatives in a facile manner.

Graphical abstract: A ligand-free solid-supported system for Sonogashira couplings: applications in nucleoside chemistry

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Article information

DOI
https://doi.org/10.1039/B505737J
Article type
Communication
Submitted
25 Apr 2005
Accepted
16 May 2005
First published
12 Aug 2005

Chem. Commun., 2005, 4551-4553

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A ligand-free solid-supported system for Sonogashira couplings: applications in nucleoside chemistry

N. K. Garg, C. C. Woodroofe, C. J. Lacenere, S. R. Quake and B. M. Stoltz, Chem. Commun., 2005, 4551 DOI: 10.1039/B505737J

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