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Issue 18, 2005
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A novel strategy for the asymmetric synthesis of chiral cyclopropane carboxaldehydes

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Abstract

A new way of combining chiral auxiliaries and substrate-directable reactions for asymmetric synthesis is described that employs a three-step sequence of aldol–cyclopropanation–retro-aldol reactions for the stereoselective synthesis of enantiopure cyclopropane carboxaldehydes.

Graphical abstract: A novel strategy for the asymmetric synthesis of chiral cyclopropane carboxaldehydes

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Publication details

The article was received on 04 Feb 2005, accepted on 04 Mar 2005 and first published on 17 Mar 2005


Article type: Communication
DOI: 10.1039/B501847A
Citation: Chem. Commun., 2005,0, 2372-2374
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    A novel strategy for the asymmetric synthesis of chiral cyclopropane carboxaldehydes

    M. Cheeseman, F. J. P. Feuillet, A. L. Johnson and S. D. Bull, Chem. Commun., 2005, 0, 2372
    DOI: 10.1039/B501847A

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