Issue 18, 2005
From the journal:

Chemical Communications

A novel strategy for the asymmetric synthesis of chiral cyclopropane carboxaldehydes†

Matt Cheeseman,a   Fred J. P. Feuillet,a   Andrew L. Johnsona  and  Steven D. Bull*a  

* Corresponding authors

a Department of Chemistry, University of Bath, Bath, UK
E-mail: s.d.bull@bath.ac.uk
Fax: (+44)-(0)1225-386231
Tel: (+44)-(0)1225-383551

Abstract

A new way of combining chiral auxiliaries and substrate-directable reactions for asymmetric synthesis is described that employs a three-step sequence of aldol–cyclopropanation–retro-aldol reactions for the stereoselective synthesis of enantiopure cyclopropane carboxaldehydes.

Graphical abstract: A novel strategy for the asymmetric synthesis of chiral cyclopropane carboxaldehydes

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Article information

DOI
https://doi.org/10.1039/B501847A
Article type
Communication
Submitted
04 Feb 2005
Accepted
04 Mar 2005
First published
17 Mar 2005

Chem. Commun., 2005, 2372-2374

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A novel strategy for the asymmetric synthesis of chiral cyclopropane carboxaldehydes

M. Cheeseman, F. J. P. Feuillet, A. L. Johnson and S. D. Bull, Chem. Commun., 2005, 2372 DOI: 10.1039/B501847A

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