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Issue 10, 2005
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A pyrimidine-like nickel(II) DNA base pair

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Abstract

4-(2′-Pyridyl)-pyrimidinone deoxyriboside is synthesized and characterized as a DNA metallo base-pair; this novel nucleoside forms a self-pair in the presence of Ni(II) and stabilizes double helical DNA to the same extent as a G·C pair.

Graphical abstract: A pyrimidine-like nickel(ii) DNA base pair

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Publication details

The article was received on 05 Oct 2004, accepted on 12 Nov 2004 and first published on 19 Jan 2005


Article type: Communication
DOI: 10.1039/B415426F
Citation: Chem. Commun., 2005, 1342-1344
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    A pyrimidine-like nickel(II) DNA base pair

    C. Switzer and D. Shin, Chem. Commun., 2005, 1342
    DOI: 10.1039/B415426F

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