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Issue 2, 2005
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A peptide-catalyzed asymmetric Stetter reaction

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Thiazolylalanine, in appropriately functionalized form, has been found to function as an enantioselective catalyst for an intramolecular Stetter reaction. Incorporation of the residue in a number of environments has resulted in a family of catalysts that promote the cyclization of a test substrate with up to 81% enantiomeric excess.

Graphical abstract: A peptide-catalyzed asymmetric Stetter reaction

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The article was received on 20 Sep 2004, accepted on 02 Nov 2004 and first published on 29 Nov 2004

Article type: Communication
DOI: 10.1039/B414574G
Citation: Chem. Commun., 2005,0, 195-197
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    A peptide-catalyzed asymmetric Stetter reaction

    S. M. Mennen, J. T. Blank, M. B. Tran-Dubé, J. E. Imbriglio and S. J. Miller, Chem. Commun., 2005, 0, 195
    DOI: 10.1039/B414574G

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