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Issue 14, 2005
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Second-generation organocatalysts for the highly enantioselective dynamic kinetic resolution of azlactones

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Abstract

Bifunctional organocatalysts of the thiourea-tert-amine type, carrying two “matched” elements of chirality, effect the alcoholytic dynamic kinetic resolution of a variety of azlactones with up to 95% ee.

Graphical abstract: Second-generation organocatalysts for the highly enantioselective dynamic kinetic resolution of azlactones

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Publication details

The article was received on 14 Dec 2004, accepted on 26 Jan 2005 and first published on 15 Feb 2005


Article type: Communication
DOI: 10.1039/B418666D
Citation: Chem. Commun., 2005,0, 1898-1900
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    Second-generation organocatalysts for the highly enantioselective dynamic kinetic resolution of azlactones

    A. Berkessel, S. Mukherjee, F. Cleemann, T. N. Müller and J. Lex, Chem. Commun., 2005, 0, 1898
    DOI: 10.1039/B418666D

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