Issue 14, 2005

Second-generation organocatalysts for the highly enantioselective dynamic kinetic resolution of azlactones

Abstract

Bifunctional organocatalysts of the thiourea-tert-amine type, carrying two “matched” elements of chirality, effect the alcoholytic dynamic kinetic resolution of a variety of azlactones with up to 95% ee.

Graphical abstract: Second-generation organocatalysts for the highly enantioselective dynamic kinetic resolution of azlactones

Supplementary files

Article information

Article type
Communication
Submitted
14 Dec 2004
Accepted
26 Jan 2005
First published
15 Feb 2005

Chem. Commun., 2005, 1898-1900

Second-generation organocatalysts for the highly enantioselective dynamic kinetic resolution of azlactones

A. Berkessel, S. Mukherjee, F. Cleemann, T. N. Müller and J. Lex, Chem. Commun., 2005, 1898 DOI: 10.1039/B418666D

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