Jump to main content
Jump to site search

Issue 12, 2005
Previous Article Next Article

Combining sugar biosynthesis genes for the generation of L- and D-amicetose and formation of two novel antitumor tetracenomycins

Author affiliations

Abstract

L- and D-stereoisomers of amicetose were generated by combining sugar biosynthesis genes from four different antibiotic gene clusters and both sugars were transferred to the elloramycin aglycone by the sugar flexible ElmGT glycosyltransferase.

Graphical abstract: Combining sugar biosynthesis genes for the generation of l- and d-amicetose and formation of two novel antitumor tetracenomycins

Back to tab navigation
Please wait while Download options loads

Supplementary files

Publication details

The article was received on 29 Nov 2004, accepted on 07 Jan 2005 and first published on 27 Jan 2005


Article type: Communication
DOI: 10.1039/B417815G
Citation: Chem. Commun., 2005, 1604-1606
  •   Request permissions

    Combining sugar biosynthesis genes for the generation of L- and D-amicetose and formation of two novel antitumor tetracenomycins

    M. Pérez, F. Lombó, L. Zhu, M. Gibson, A. F. Braña, J. Rohr, J. A. Salas and C. Méndez, Chem. Commun., 2005, 1604
    DOI: 10.1039/B417815G

Search articles by author