Issue 5, 2005
From the journal:

Chemical Communications

Photolithographic synthesis of cyclic peptide arrays using a differential deprotection strategy†

Shuwei Li,a   Nishanth Marthandan,a   Dawn Bowerman,a   Harold R. Garnera  and  Thomas Kodadek*a  

* Corresponding authors

a Departments of Internal Medicine and Molecular Biology and the Center for Biomedical Inventions, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX, USA
E-mail: thomas.kodadek@utsouthwestern.edu

Abstract

We report here a strategy for the photolithographic synthesis of diverse, spatially addressable arrays of cyclic peptides which employs a differential deprotection strategy for the combinatorial addition of side chains to a pre-fabricated cyclic core.

Graphical abstract: Photolithographic synthesis of cyclic peptide arrays using a differential deprotection strategy

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Article information

DOI
https://doi.org/10.1039/B415578E
Article type
Communication
Submitted
08 Oct 2004
Accepted
30 Nov 2004
First published
05 Jan 2005

Chem. Commun., 2005, 581-583

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Photolithographic synthesis of cyclic peptide arrays using a differential deprotection strategy

S. Li, N. Marthandan, D. Bowerman, H. R. Garner and T. Kodadek, Chem. Commun., 2005, 581 DOI: 10.1039/B415578E

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