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Issue 19, 2004
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Loops on loops: generation of complex scaffolded peptides presenting multiple cyclic fragments

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Abstract

Scaffolded peptides presenting two different cyclic peptide fragments through a cyclic peptidomimetic scaffold in a site-selective fashion, were generated by stepwise solid phase synthesis and fragment condensation in parallel, demonstrating that either strategy is adequate to generate complex scaffolded peptides.

Graphical abstract: Loops on loops: generation of complex scaffolded peptides presenting multiple cyclic fragments

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Publication details

The article was received on 11 Mar 2004, accepted on 09 Aug 2004 and first published on 06 Sep 2004


Article type: Paper
DOI: 10.1039/B403720K
Citation: Org. Biomol. Chem., 2004,2, 2847-2851
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    Loops on loops: generation of complex scaffolded peptides presenting multiple cyclic fragments

    R. Franke, C. Doll, V. Wray and J. Eichler, Org. Biomol. Chem., 2004, 2, 2847
    DOI: 10.1039/B403720K

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