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Issue 22, 2004
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Synthesis of ring-oxidized retinoids as substrates of mouse class I alcohol dehydrogenase (ADH1)

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Abstract

Ring-oxidized retinoids have been synthesized stereoselectively using the Stille cross-coupling reaction. Kinetic constants of mouse class I alcohol dehydrogenase (ADH1) with these retinoids were determined.

Graphical abstract: Synthesis of ring-oxidized retinoids as substrates of mouse class I alcohol dehydrogenase (ADH1)

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Publication details

The article was received on 29 Jul 2004, accepted on 15 Sep 2004 and first published on 11 Oct 2004


Article type: Paper
DOI: 10.1039/B411585F
Citation: Org. Biomol. Chem., 2004,2, 3368-3373
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    Synthesis of ring-oxidized retinoids as substrates of mouse class I alcohol dehydrogenase (ADH1)

    M. Domínguez, R. Alvarez, S. Martras, J. Farrés, X. Parés and A. R. de Lera, Org. Biomol. Chem., 2004, 2, 3368
    DOI: 10.1039/B411585F

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