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Issue 15, 2004
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A Suzuki–Miyaura coupling mediated deprotection as key to the synthesis of a fully lipidated malarial GPI disaccharide

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Abstract

Ligandless palladium-catalyzed Suzuki–Miyaura coupling converted an inert p-bromobenzyl ether to a DDQ-labile p-(3,4-dimethoxyphenyl) benzyl ether in the presence of azide functionality and this strategy serves as a key step for the convergent synthesis of a fully lipidated malaria GPI disaccharide.

Graphical abstract: A Suzuki–Miyaura coupling mediated deprotection as key to the synthesis of a fully lipidated malarial GPI disaccharide

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Publication details

The article was received on 14 May 2004, accepted on 09 Jun 2004 and first published on 09 Jul 2004


Article type: Communication
DOI: 10.1039/B407324J
Citation: Chem. Commun., 2004,0, 1708-1709
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    A Suzuki–Miyaura coupling mediated deprotection as key to the synthesis of a fully lipidated malarial GPI disaccharide

    X. Liu and P. H. Seeberger, Chem. Commun., 2004, 0, 1708
    DOI: 10.1039/B407324J

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