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Issue 7, 2004
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Solvent-drop grinding: green polymorph control of cocrystallisation

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Abstract

By grinding with a minimal addition of a solvent of appropriate polarity, control over the polymorphic outcome of a novel cocrystallisation involving the model pharmaceutical compound caffeine may be achieved.

Graphical abstract: Solvent-drop grinding: green polymorph control of cocrystallisation

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Publication details

The article was received on 21 Jan 2004, accepted on 20 Feb 2004 and first published on 05 Mar 2004


Article type: Communication
DOI: 10.1039/B400978A
Citation: Chem. Commun., 2004,0, 890-891
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    Solvent-drop grinding: green polymorph control of cocrystallisation

    A. V. Trask, W. D. S. Motherwell and W. Jones, Chem. Commun., 2004, 0, 890
    DOI: 10.1039/B400978A

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