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Issue 6, 2004
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Stereochemical determination of dictyostatin, a novel microtubule-stabilising macrolide from the marine sponge Corallistidae sp.

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Abstract

The relative stereochemistry of the 22-membered marine macrolide dictyostatin, a Taxol-like antimitotic agent, was determined based on a combination of extensive high field NMR studies, including J-based configuration analysis, and molecular modelling.

Graphical abstract: Stereochemical determination of dictyostatin, a novel microtubule-stabilising macrolide from the marine sponge Corallistidae sp.

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Publication details

The article was received on 16 Dec 2003, accepted on 26 Jan 2004 and first published on 09 Feb 2004


Article type: Communication
DOI: 10.1039/B316390C
Citation: Chem. Commun., 2004,0, 632-633
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    Stereochemical determination of dictyostatin, a novel microtubule-stabilising macrolide from the marine sponge Corallistidae sp.

    I. Paterson, R. Britton, O. Delgado and A. E. Wright, Chem. Commun., 2004, 0, 632
    DOI: 10.1039/B316390C

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