Issue 10, 2004
From the journal:

Chemical Communications

Efficient synthesis of a nucleoside-diphospho-exo-glycal displaying time-dependent inactivation of UDP-galactopyranose mutase†

Audrey Caravano,a   Stéphane P. Vincent*a  and  Pierre Sinaÿ*a  

* Corresponding authors

a Ecole Normale Supérieure, Département de Chimie, UMR-8642 du CNRS, 24 rue Lhomond, 75231 Paris Cedex 05, France
E-mail: pierre.sinay@ens.fr
Fax: 33 (0)1 44 32 33 97

Abstract

A short and efficient synthesis of UDP-exo-galactofuranosyl-glycal is presented. This molecule displayed an interesting time-dependent inactivation of UDP-galactopyranose mutase, an essential enzyme of the mycobacterial cell wall biosynthesis.

Graphical abstract: Efficient synthesis of a nucleoside-diphospho-exo-glycal displaying time-dependent inactivation of UDP-galactopyranose mutase

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Article information

DOI
https://doi.org/10.1039/B402469A
Article type
Communication
Submitted
18 Feb 2004
Accepted
29 Mar 2004
First published
23 Apr 2004

Chem. Commun., 2004, 1216-1217

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Efficient synthesis of a nucleoside-diphospho-exo-glycal displaying time-dependent inactivation of UDP-galactopyranose mutase

A. Caravano, S. P. Vincent and P. Sinaÿ, Chem. Commun., 2004, 1216 DOI: 10.1039/B402469A

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