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Issue 9, 2004
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An iterative approach to novel polyamines via nucleophilic ring-opening of aziridinium ions with β-amino alcohols

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Abstract

An iterative procedure for the synthesis of a novel class of synthetic polyamines has been developed, utilising the regioselective ring-opening of aziridinium ion intermediates; facile N-allyl deprotection of intermediate polyamines allows the rapid construction of high molecular weight, stereochemically defined compounds in a convergent manner.

Graphical abstract: An iterative approach to novel polyamines via nucleophilic ring-opening of aziridinium ions with β-amino alcohols

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Publication details

The article was received on 02 Feb 2004, accepted on 09 Mar 2004 and first published on 01 Apr 2004


Article type: Communication
DOI: 10.1039/B401447B
Citation: Chem. Commun., 2004,0, 1080-1081
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    An iterative approach to novel polyamines via nucleophilic ring-opening of aziridinium ions with β-amino alcohols

    C. McKay, R. J. Wilson and C. M. Rayner, Chem. Commun., 2004, 0, 1080
    DOI: 10.1039/B401447B

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