Issue 6, 2004
From the journal:

Analyst

Very high pressure HPLC with 1 mm id columns

Luis A. Colón,*a   José M. Cintrón,†a   Jason A. Anspach,a   Adam M. Fermierb  and  Kelly A. Swinneyb  

* Corresponding authors

a Department of Chemistry, University at Buffalo, The State University of New York, NS Complex, Buffalo, New York, USA
E-mail: lacolon@buffalo.edu
Fax: 1-716-645-6963
Tel: 1-716-645-6800

b Johnson & Johnson Pharmaceutical Research and Development, Science and New Technology/Analytical Development, Raritan, NJ 08869, USA

Abstract

Theoretical calculations and experimental data indicate that very high pressure HPLC can be performed using 1 and 1.5 mm id columns, and contrary to previous beliefs, the frictional heating generated does not appear to be detrimental to the separation.

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Article information

DOI
https://doi.org/10.1039/B405242K
Article type
Communication
Submitted
07 Apr 2004
Accepted
15 Apr 2004
First published
28 Apr 2004

Analyst, 2004,129, 503-504

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Very high pressure HPLC with 1 mm id columns

L. A. Colón, J. M. Cintrón, J. A. Anspach, A. M. Fermier and K. A. Swinney, Analyst, 2004, 129, 503 DOI: 10.1039/B405242K

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