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Issue 14, 2003
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Convergent synthesis and preliminary biological evaluations of the stilbenolignan (±)-aiphanol and various congeners

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Abstract

Treatment of an equimolar mixture of stilbene 7 and cinnamyl alcohol 8 with silver carbonate in acetonebenzene afforded a ca. 2 : 1 : 2 : 1 mixture of the stilbenolignan (±)-aiphanol (1) and congeners 2–4 each of which show significant anti-angiogenic and COX-2 inhibitory properties.

Graphical abstract: Convergent synthesis and preliminary biological evaluations of the stilbenolignan (±)-aiphanol and various congeners

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Publication details

The article was received on 09 May 2003, accepted on 13 Jun 2003 and first published on 23 Jun 2003


Article type: Communication
DOI: 10.1039/B305106D
Citation: Org. Biomol. Chem., 2003,1, 2427-2429
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    Convergent synthesis and preliminary biological evaluations of the stilbenolignan (±)-aiphanol and various congeners

    M. G. Banwell, A. Bezos, S. Chand, G. Dannhardt, W. Kiefer, U. Nowe, C. R. Parish, G. Paul Savage and H. Ulbrich, Org. Biomol. Chem., 2003, 1, 2427
    DOI: 10.1039/B305106D

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