A novel Gd(III) complex, GdDOTA-(BOM)4, has been prepared by a simple three-step procedure. The complex showed high T1-relaxivity values in serum albumin solutions, blood and plasma, resulting from high affinity for serum albumin. The T1-relaxivity in plasma, 67.4 s−1 mM−1 (20 MHz, 37 °C), makes it a promising candidate for angiographic applications of MRI.
R. Hovland, A. J. Aasen and J. Klaveness, Org. Biomol. Chem., 2003, 1, 1707 DOI: 10.1039/B301944F
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