Enzymatic degradation of poly(R,S-3-hydroxybutanoate) to cyclic oligomers under continuous flow†
Abstract
The enzymatic degradation of chemically synthesized poly(R,S-3-hydroxybutanoate)
(PHB) to a reactive cyclic oligomer under continuous flow using an enzyme column was studied and directed towards green chemical recycling. It was confirmed that atactic and syndiotactic PHBs were quantitatively transformed into the corresponding cyclic oligomer by passing through a column packed with immobilized lipase from Candida antarctica
(Novozym 435) at 40 °C using