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Issue 6, 2003
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Chemical modification of mammalian cell surfaces

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The mammalian cell surface is a highly heterogeneous chemical environment with proteins, carbohydrates, lipids and composite molecules controlling vital cell functions. Chemical modification of this environment is a challenge due to the complexity of the surface chemistry and the fragility of the cell. Here, we review recent attempts to perform targeted, non-genetically controlled, changes to cell surface chemistry. Potential applications of cell surface engineering are presented.

Graphical abstract: Chemical modification of mammalian cell surfaces

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The article was received on 29 Apr 2003 and first published on 24 Jul 2003

Article type: Tutorial Review
DOI: 10.1039/B211643J
Citation: Chem. Soc. Rev., 2003,32, 327-337
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    Chemical modification of mammalian cell surfaces

    B. Kellam, P. A. De Bank and K. M. Shakesheff, Chem. Soc. Rev., 2003, 32, 327
    DOI: 10.1039/B211643J

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