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Issue 7, 2003
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Highly efficient Lewis acid-catalysed Pictet–Spengler reactions discovered by parallel screening

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Abstract

High yielding Lewis acid-catalysed one-pot Pictet–Spengler reactions of tryptophan methyl ester and tryptamine with aliphatic and aromatic aldehydes were achieved in short reaction times with the aid of microwave irradiation.

Graphical abstract: Highly efficient Lewis acid-catalysed Pictet–Spengler reactions discovered by parallel screening

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Publication details

The article was received on 05 Dec 2002, accepted on 19 Feb 2003 and first published on 11 Mar 2003


Article type: Communication
DOI: 10.1039/B212063A
Citation: Chem. Commun., 2003,0, 916-917
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    Highly efficient Lewis acid-catalysed Pictet–Spengler reactions discovered by parallel screening

    N. Srinivasan and A. Ganesan, Chem. Commun., 2003, 0, 916
    DOI: 10.1039/B212063A

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