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Issue 24, 2003
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Fluorescence detection of guanine–adenine transition by a hydrogen bond forming small compound

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Abstract

In combination with abasic site-containing oligodeoxynucleotides, 2-amino-4-oxopteridine (pterin) can selectively recognize guanine base over other nucleobases accompanied by fluorescence quenching, which allows clear detection of a guanine–adenine transition with the naked eye.

Graphical abstract: Fluorescence detection of guanine–adenine transition by a hydrogen bond forming small compound

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Publication details

The article was received on 06 Aug 2003, accepted on 02 Oct 2003 and first published on 31 Oct 2003


Article type: Communication
DOI: 10.1039/B309229A
Citation: Chem. Commun., 2003,0, 2960-2961
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    Fluorescence detection of guanine–adenine transition by a hydrogen bond forming small compound

    K. Yoshimoto, C. Xu, S. Nishizawa, T. Haga, H. Satake and N. Teramae, Chem. Commun., 2003, 0, 2960
    DOI: 10.1039/B309229A

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