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Issue 6, 2002
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Efficient regioselective synthesis of triheterocyclic compounds: imidazo[2,1-b]benzothiazoles, pyrimido[2,1-b]benzothiazolones and pyrimido[2,1-b]benzothiazoles

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Abstract

The preparation and characterisation of triheterocyclic compounds, via annulation reactions, are described. Amidines 1 reacted with substituted bromomethyl compounds, acid chlorides, and acrylic dienophiles to afford the corresponding imidazo[2,1-b]benzothiazoles 2 and pyrimido[2,1-b]benzothiazoles 3 or 4.

Graphical abstract: Efficient regioselective synthesis of triheterocyclic compounds: imidazo[2,1-b]benzothiazoles, pyrimido[2,1-b]benzothiazolones and pyrimido[2,1-b]benzothiazoles

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Publication details

The article was received on 21 Dec 2001, accepted on 05 Feb 2002 and first published on 22 Feb 2002


Article type: Paper
DOI: 10.1039/B111639H
Citation: J. Chem. Soc., Perkin Trans. 1, 2002, 741-745
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    Efficient regioselective synthesis of triheterocyclic compounds: imidazo[2,1-b]benzothiazoles, pyrimido[2,1-b]benzothiazolones and pyrimido[2,1-b]benzothiazoles

    C. Landreau, D. Deniaud, M. Evain, A. Reliquet and J. Meslin, J. Chem. Soc., Perkin Trans. 1, 2002, 741
    DOI: 10.1039/B111639H

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