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Issue 4, 2002
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Bacterial chromosome extraction and isolation

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Abstract

We have used diffusive mixing and dielectrophoretic trapping to lyse Escherichia coli cells in a microfabricated environment and trap the E. coli chromosome. We characterize the conditions needed for efficient lysis of the cells, and conditions needed for the dielectrophoretic trapping of the chromatin without the trapping of cytoplasmic proteins.

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Publication details

The article was received on 15 Aug 2002, accepted on 24 Oct 2002 and first published on 07 Nov 2002


Article type: Paper
DOI: 10.1039/B208010A
Citation: Lab Chip, 2002,2, 207-212
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    Bacterial chromosome extraction and isolation

    C. Prinz, J. O. Tegenfeldt, R. H. Austin, E. C. Cox and J. C. Sturm, Lab Chip, 2002, 2, 207
    DOI: 10.1039/B208010A

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