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Issue 2, 2002
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An evaporation-based microfluidic sample concentration method

Glenn M. Walkera  and  David J. Beebe*a 
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* Corresponding authors

a Biomedical Engineering Department, University of Wisconsin-Madison, Madison, USA
E-mail: dbeebe@engr.wisc.edu

Abstract

We present a method for sample concentration within microfluidic devices using evaporation-induced flow. Evaporation-induced flow is easy to incorporate into microfluidic designs and can be used to concentrate a wide variety of molecules. The practicality of this method was demonstrated with 0.2 μm fluorescent spheres and FITC-labeled BSA. Thirty two percent of the 0.6 μL fluorescent sphere suspension was concentrated into a well within a microfluidic device. In the same amount of time, 93% of the 0.6 μL FITC-labeled BSA solution was concentrated.

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Publication details

The article was received on 11 Mar 2002, accepted on 15 Apr 2002 and first published on 30 Apr 2002


Article type: Communication
DOI: 10.1039/B202473J
Citation: Lab Chip, 2002,2, 57-61
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    An evaporation-based microfluidic sample concentration method

    G. M. Walker and D. J. Beebe, Lab Chip, 2002, 2, 57
    DOI: 10.1039/B202473J

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